AKT1 substrate 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
25077541 MEF Mouse NO
31945054 IMR-90 Human YES

GO terms:

Biological Process:
negative regulation of protein kinase activity [GO:0006469],
Notch signaling pathway [GO:0007219],
negative regulation of TOR signaling [GO:0032007],
regulation of apoptotic process [GO:0042981],
regulation of neuron apoptotic process [GO:0043523],
negative regulation of cell size [GO:0045792],
neurotrophin TRK receptor signaling pathway [GO:0048011],
regulation of cellular response to heat [GO:1900034],

Molecular Function:
protein binding [GO:0005515],

Cellular Component:
nucleus [GO:0005634],
cytoplasm [GO:0005737],
cytosol [GO:0005829],
TORC1 complex [GO:0031931],
macromolecular complex [GO:0032991],
nucleoplasm [GO:0005654],