AKR1C4
aldo-keto reductase family 1 member C4
Link to human orthologSearch for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
Pubmed ID | Cell line | Tissue | Source | High-throughput |
31945054 | IMR-90 | Human | YES |
GO terms:
Biological Process:
retinoid metabolic process [GO:0001523],
prostaglandin metabolic process [GO:0006693],
bile acid biosynthetic process [GO:0006699],
steroid metabolic process [GO:0008202],
C21-steroid hormone metabolic process [GO:0008207],
androgen metabolic process [GO:0008209],
bile acid and bile salt transport [GO:0015721],
electron transport chain [GO:0022900],
progesterone metabolic process [GO:0042448],
daunorubicin metabolic process [GO:0044597],
doxorubicin metabolic process [GO:0044598],
cellular response to jasmonic acid stimulus [GO:0071395],
Molecular Function:
retinal dehydrogenase activity [GO:0001758],
alditol:NADP+ 1-oxidoreductase activity [GO:0004032],
aldo-keto reductase (NADP) activity [GO:0004033],
steroid binding [GO:0005496],
alcohol dehydrogenase (NADP+) activity [GO:0008106],
electron carrier activity [GO:0009055],
bile acid transmembrane transporter activity [GO:0015125],
steroid dehydrogenase activity [GO:0016229],
oxidoreductase activity [GO:0016491],
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655],
bile acid binding [GO:0032052],
androsterone dehydrogenase activity [GO:0047023],
ketosteroid monooxygenase activity [GO:0047086],
chlordecone reductase activity [GO:0047743],
Cellular Component:
cytoplasm [GO:0005737],
cytosol [GO:0005829],
extracellular exosome [GO:0070062],