EFNA1

ephrin A1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
negative regulation of transcription from RNA polymerase II promoter [GO:0000122],
angiogenesis [GO:0001525],
positive regulation of protein phosphorylation [GO:0001934],
aortic valve morphogenesis [GO:0003180],
mitral valve morphogenesis [GO:0003183],
endocardial cushion to mesenchymal transition involved in heart valve formation [GO:0003199],
cell-cell signaling [GO:0007267],
axon guidance [GO:0007411],
negative regulation of epithelial to mesenchymal transition [GO:0010719],
notochord formation [GO:0014028],
cell migration [GO:0016477],
regulation of cell adhesion mediated by integrin [GO:0033628],
substrate adhesion-dependent cell spreading [GO:0034446],
negative regulation of MAPK cascade [GO:0043409],
positive regulation of MAPK cascade [GO:0043410],
regulation of blood vessel endothelial cell migration [GO:0043535],
regulation of angiogenesis [GO:0045765],
ephrin receptor signaling pathway [GO:0048013],
regulation of peptidyl-tyrosine phosphorylation [GO:0050730],
positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731],
regulation of axonogenesis [GO:0050770],
protein stabilization [GO:0050821],
negative regulation of dendritic spine morphogenesis [GO:0061002],
positive regulation of protein tyrosine kinase activity [GO:0061098],
negative regulation of thymocyte apoptotic process [GO:0070244],
positive regulation of beta-amyloid formation [GO:1902004],
positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961],
negative regulation of proteolysis involved in cellular protein catabolic process [GO:1903051],
neuron differentiation [GO:0030182],

Molecular Function:
receptor binding [GO:0005102],
protein binding [GO:0005515],
ephrin receptor binding [GO:0046875],

Cellular Component:
extracellular region [GO:0005576],
plasma membrane [GO:0005886],
anchored component of plasma membrane [GO:0046658],
membrane [GO:0016020],
anchored component of membrane [GO:0031225],