ECH1

enoyl-CoA hydratase 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31983656 MSC Human YES

GO terms:

Biological Process:
protein targeting to peroxisome [GO:0006625],
fatty acid beta-oxidation [GO:0006635],
lipid metabolic process [GO:0006629],
fatty acid metabolic process [GO:0006631],

Molecular Function:
protein binding [GO:0005515],
delta3,5-delta2,4-dienoyl-CoA isomerase activity [GO:0051750],
catalytic activity [GO:0003824],
isomerase activity [GO:0016853],

Cellular Component:
mitochondrion [GO:0005739],
peroxisome [GO:0005777],
peroxisomal matrix [GO:0005782],
cytosol [GO:0005829],
membrane [GO:0016020],
extracellular exosome [GO:0070062],