ECE2

endothelin converting enzyme 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
29548335 Saos-2 Human YES

GO terms:

Biological Process:
cell-cell signaling [GO:0007267],
peptide hormone processing [GO:0016486],
methylation [GO:0032259],
proteolysis [GO:0006508],

Molecular Function:
metalloendopeptidase activity [GO:0004222],
methyltransferase activity [GO:0008168],
metal ion binding [GO:0046872],
peptidase activity [GO:0008233],
metallopeptidase activity [GO:0008237],
hydrolase activity [GO:0016787],

Cellular Component:
Golgi membrane [GO:0000139],
integral component of membrane [GO:0016021],
transport vesicle membrane [GO:0030658],
cytoplasmic vesicle membrane [GO:0030659],
Golgi apparatus [GO:0005794],
trans-Golgi network [GO:0005802],
membrane [GO:0016020],
cytoplasmic vesicle [GO:0031410],