AKIRIN2
akirin 2
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Down-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 29321003 | Primary bronchial epithelial cells derived from lung | Human | YES | |
GO terms:
Biological Process:
negative regulation of transcription from RNA polymerase II promoter [GO:0000122],
positive regulation of cell proliferation [GO:0008284],
embryo development ending in birth or egg hatching [GO:0009792],
positive regulation of endopeptidase activity [GO:0010950],
response to lipopolysaccharide [GO:0032496],
positive regulation of interleukin-6 production [GO:0032755],
innate immune response [GO:0045087],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],
immune system process [GO:0002376],
multicellular organism development [GO:0007275],
negative regulation of gene expression [GO:0010629],
negative regulation of transcription, DNA-templated [GO:0045892],
Molecular Function:
protein binding [GO:0005515],
enzyme binding [GO:0019899],
Cellular Component:
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
transcriptional repressor complex [GO:0017053],