DST

dystonin

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
31945054 IMR-90 Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
cytoskeleton organization [GO:0007010],
cell adhesion [GO:0007155],
integrin-mediated signaling pathway [GO:0007229],
retrograde axonal transport [GO:0008090],
response to wounding [GO:0009611],
maintenance of cell polarity [GO:0030011],
cytoplasmic microtubule organization [GO:0031122],
hemidesmosome assembly [GO:0031581],
wound healing [GO:0042060],
intermediate filament cytoskeleton organization [GO:0045104],
cell motility [GO:0048870],
axonogenesis [GO:0007409],
regulation of microtubule polymerization or depolymerization [GO:0031110],
intracellular transport [GO:0046907],

Molecular Function:
actin binding [GO:0003779],
integrin binding [GO:0005178],
structural molecule activity [GO:0005198],
calcium ion binding [GO:0005509],
protein binding [GO:0005515],
microtubule binding [GO:0008017],
protein C-terminus binding [GO:0008022],
microtubule plus-end binding [GO:0051010],
cytoskeletal protein binding [GO:0008092],
protein homodimerization activity [GO:0042803],
metal ion binding [GO:0046872],

Cellular Component:
basement membrane [GO:0005604],
nucleus [GO:0005634],
nuclear envelope [GO:0005635],
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],
endoplasmic reticulum membrane [GO:0005789],
cytosol [GO:0005829],
intermediate filament [GO:0005882],
focal adhesion [GO:0005925],
cell cortex [GO:0005938],
basal plasma membrane [GO:0009925],
microtubule cytoskeleton [GO:0015630],
membrane [GO:0016020],
integral component of membrane [GO:0016021],
Z disc [GO:0030018],
hemidesmosome [GO:0030056],
cell leading edge [GO:0031252],
cytoplasmic vesicle [GO:0031410],
H zone [GO:0031673],
microtubule plus-end [GO:0035371],
axon cytoplasm [GO:1904115],
stress fiber [GO:0001725],
endoplasmic reticulum [GO:0005783],
cytoskeleton [GO:0005856],
microtubule [GO:0005874],
plasma membrane [GO:0005886],
cytoplasmic side of plasma membrane [GO:0009898],
postsynaptic density [GO:0014069],
intercalated disc [GO:0014704],
actin cytoskeleton [GO:0015629],
cell junction [GO:0030054],
axon [GO:0030424],
sarcolemma [GO:0042383],
cell projection [GO:0042995],
perinuclear region of cytoplasm [GO:0048471],
neurofilament cytoskeleton [GO:0060053],
perinuclear endoplasmic reticulum [GO:0097038],