DPEP1

dipeptidase 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 Skin, Lung Human YES
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
proteolysis [GO:0006508],
lipid metabolic process [GO:0006629],
leukotriene metabolic process [GO:0006691],
glutathione metabolic process [GO:0006749],
glutathione catabolic process [GO:0006751],
xenobiotic metabolic process [GO:0006805],
apoptotic process [GO:0006915],
inflammatory response [GO:0006954],
antibiotic metabolic process [GO:0016999],
negative regulation of cell migration [GO:0030336],
neutrophil chemotaxis [GO:0030593],
cellular response to drug [GO:0035690],
negative regulation of apoptotic process [GO:0043066],
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154],
homocysteine metabolic process [GO:0050667],
cellular response to calcium ion [GO:0071277],
cellular response to nitric oxide [GO:0071732],
cellular lactam catabolic process [GO:0072340],

Molecular Function:
protein binding [GO:0005515],
metalloexopeptidase activity [GO:0008235],
dipeptidyl-peptidase activity [GO:0008239],
zinc ion binding [GO:0008270],
beta-lactamase activity [GO:0008800],
GPI anchor binding [GO:0034235],
cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027],
metallodipeptidase activity [GO:0070573],
modified amino acid binding [GO:0072341],
peptidase activity [GO:0008233],
metallopeptidase activity [GO:0008237],
hydrolase activity [GO:0016787],
dipeptidase activity [GO:0016805],
metal ion binding [GO:0046872],

Cellular Component:
extracellular space [GO:0005615],
nucleoplasm [GO:0005654],
plasma membrane [GO:0005886],
apical plasma membrane [GO:0016324],
cell junction [GO:0030054],
anchored component of membrane [GO:0031225],
microvillus membrane [GO:0031528],
apical part of cell [GO:0045177],
extracellular exosome [GO:0070062],
membrane [GO:0016020],
cell projection [GO:0042995],