AK3

adenylate kinase 3

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31983656 MSC Human YES

GO terms:

Biological Process:
purine nucleotide metabolic process [GO:0006163],
ADP biosynthetic process [GO:0006172],
blood coagulation [GO:0007596],
nucleoside triphosphate biosynthetic process [GO:0009142],
phosphorylation [GO:0016310],
AMP metabolic process [GO:0046033],
GTP metabolic process [GO:0046039],
ITP metabolic process [GO:0046041],
UTP metabolic process [GO:0046051],
nucleoside monophosphate phosphorylation [GO:0046940],
nucleobase-containing compound metabolic process [GO:0006139],
AMP phosphorylation [GO:0006756],
ATP metabolic process [GO:0046034],
dATP metabolic process [GO:0046060],

Molecular Function:
adenylate kinase activity [GO:0004017],
protein binding [GO:0005515],
ATP binding [GO:0005524],
GTP binding [GO:0005525],
nucleoside triphosphate adenylate kinase activity [GO:0046899],
nucleotide binding [GO:0000166],
kinase activity [GO:0016301],
transferase activity [GO:0016740],
phosphotransferase activity, phosphate group as acceptor [GO:0016776],
nucleobase-containing compound kinase activity [GO:0019205],
identical protein binding [GO:0042802],

Cellular Component:
cytoplasm [GO:0005737],
mitochondrion [GO:0005739],
mitochondrial matrix [GO:0005759],
mitochondrial intermembrane space [GO:0005758],