DMTN

dematin actin binding protein

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
cytoskeleton organization [GO:0007010],
regulation of cell shape [GO:0008360],
regulation of lamellipodium assembly [GO:0010591],
positive regulation of fibroblast migration [GO:0010763],
negative regulation of peptidyl-threonine phosphorylation [GO:0010801],
negative regulation of cell-substrate adhesion [GO:0010812],
lamellipodium assembly [GO:0030032],
actin cytoskeleton organization [GO:0030036],
positive regulation of blood coagulation [GO:0030194],
regulation of actin cytoskeleton organization [GO:0032956],
negative regulation of peptidyl-serine phosphorylation [GO:0033137],
calcium-mediated signaling using intracellular calcium source [GO:0035584],
calcium-mediated signaling using extracellular calcium source [GO:0035585],
erythrocyte development [GO:0048821],
negative regulation of peptidyl-tyrosine phosphorylation [GO:0050732],
actin filament bundle assembly [GO:0051017],
regulation of filopodium assembly [GO:0051489],
actin filament capping [GO:0051693],
negative regulation of focal adhesion assembly [GO:0051895],
transmembrane transport [GO:0055085],
macromolecular complex assembly [GO:0065003],
protein secretion by platelet [GO:0070560],
cellular response to calcium ion [GO:0071277],
cellular response to cAMP [GO:0071320],
positive regulation of wound healing [GO:0090303],
negative regulation of protein targeting to membrane [GO:0090315],
actin filament reorganization [GO:0090527],
negative regulation of substrate adhesion-dependent cell spreading [GO:1900025],
positive regulation of substrate adhesion-dependent cell spreading [GO:1900026],
positive regulation of platelet aggregation [GO:1901731],
positive regulation of integrin-mediated signaling pathway [GO:2001046],

Molecular Function:
actin binding [GO:0003779],
receptor binding [GO:0005102],
protein binding [GO:0005515],
spectrin binding [GO:0030507],
protein self-association [GO:0043621],
actin filament binding [GO:0051015],

Cellular Component:
cytosol [GO:0005829],
actin filament [GO:0005884],
plasma membrane [GO:0005886],
endomembrane system [GO:0012505],
postsynaptic density [GO:0014069],
spectrin-associated cytoskeleton [GO:0014731],
actin cytoskeleton [GO:0015629],
cortical cytoskeleton [GO:0030863],
platelet dense tubular network membrane [GO:0031095],
cell projection membrane [GO:0031253],
cytoplasmic vesicle [GO:0031410],
perinuclear region of cytoplasm [GO:0048471],
cytoplasm [GO:0005737],
cytoskeleton [GO:0005856],
membrane [GO:0016020],
cell projection [GO:0042995],