AK2

adenylate kinase 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
purine nucleotide metabolic process [GO:0006163],
ADP biosynthetic process [GO:0006172],
nucleoside diphosphate metabolic process [GO:0009132],
nucleobase-containing small molecule interconversion [GO:0015949],
phosphorylation [GO:0016310],
AMP metabolic process [GO:0046033],
ATP metabolic process [GO:0046034],
nucleoside monophosphate phosphorylation [GO:0046940],
nucleobase-containing compound metabolic process [GO:0006139],
dATP metabolic process [GO:0046060],

Molecular Function:
adenylate kinase activity [GO:0004017],
ATP binding [GO:0005524],
nucleotide binding [GO:0000166],
kinase activity [GO:0016301],
transferase activity [GO:0016740],
phosphotransferase activity, phosphate group as acceptor [GO:0016776],
nucleobase-containing compound kinase activity [GO:0019205],

Cellular Component:
cytoplasm [GO:0005737],
mitochondrion [GO:0005739],
mitochondrial intermembrane space [GO:0005758],
extracellular exosome [GO:0070062],
nucleus [GO:0005634],
mitochondrial inner membrane [GO:0005743],
cytosol [GO:0005829],
sperm flagellum [GO:0036126],
sperm mitochondrial sheath [GO:0097226],