DMGDH

dimethylglycine dehydrogenase

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES
31945125 Primary astrocytes derived from brain Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
amino-acid betaine catabolic process [GO:0006579],
choline metabolic process [GO:0019695],
electron transport chain [GO:0022900],
choline catabolic process [GO:0042426],
tetrahydrofolate interconversion [GO:0035999],
oxidation-reduction process [GO:0055114],

Molecular Function:
RNA binding [GO:0003723],
electron carrier activity [GO:0009055],
oxidoreductase activity [GO:0016491],
dimethylglycine dehydrogenase activity [GO:0047865],
folic acid binding [GO:0005542],
flavin adenine dinucleotide binding [GO:0050660],

Cellular Component:
cytoplasm [GO:0005737],
mitochondrion [GO:0005739],
mitochondrial matrix [GO:0005759],