AK1
adenylate kinase 1
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 28844647 | BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 | Skin, Lung | Human | YES |
| 31945125 | Primary astrocytes derived from brain | Human | YES | |
Status in senescence: Down-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 31983656 | MSC | Human | YES | |
| 33296652 | heart | heart | Human | NO |
GO terms:
Biological Process:
purine nucleotide metabolic process [GO:0006163],
nucleoside diphosphate phosphorylation [GO:0006165],
ADP biosynthetic process [GO:0006172],
nucleoside triphosphate biosynthetic process [GO:0009142],
nucleobase-containing small molecule interconversion [GO:0015949],
AMP metabolic process [GO:0046033],
ATP metabolic process [GO:0046034],
nucleoside monophosphate phosphorylation [GO:0046940],
nucleobase-containing compound metabolic process [GO:0006139],
cell cycle arrest [GO:0007050],
positive regulation of glucose transport [GO:0010828],
phosphorylation [GO:0016310],
inosine biosynthetic process [GO:0046103],
Molecular Function:
adenylate kinase activity [GO:0004017],
nucleoside diphosphate kinase activity [GO:0004550],
ATP binding [GO:0005524],
nucleotide binding [GO:0000166],
kinase activity [GO:0016301],
transferase activity [GO:0016740],
phosphotransferase activity, phosphate group as acceptor [GO:0016776],
nucleobase-containing compound kinase activity [GO:0019205],
Cellular Component:
cytoplasm [GO:0005737],
cytosol [GO:0005829],
extracellular exosome [GO:0070062],
outer dense fiber [GO:0001520],
plasma membrane [GO:0005886],
sarcomere [GO:0030017],
sperm flagellum [GO:0036126],
neuron projection [GO:0043005],
perinuclear region of cytoplasm [GO:0048471],