AIMP1

aminoacyl tRNA synthetase complex interacting multifunctional protein 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31983656 MSC Human YES

GO terms:

Biological Process:
angiogenesis [GO:0001525],
negative regulation of endothelial cell proliferation [GO:0001937],
tRNA aminoacylation for protein translation [GO:0006418],
apoptotic process [GO:0006915],
inflammatory response [GO:0006954],
signal transduction [GO:0007165],
cell-cell signaling [GO:0007267],
leukocyte migration [GO:0050900],
defense response to virus [GO:0051607],
positive regulation of glucagon secretion [GO:0070094],
translation [GO:0006412],

Molecular Function:
tRNA binding [GO:0000049],
cytokine activity [GO:0005125],
protein binding [GO:0005515],
protein homodimerization activity [GO:0042803],
GTPase binding [GO:0051020],
RNA binding [GO:0003723],

Cellular Component:
extracellular space [GO:0005615],
nucleus [GO:0005634],
endoplasmic reticulum [GO:0005783],
Golgi apparatus [GO:0005794],
cytosol [GO:0005829],
cell surface [GO:0009986],
membrane [GO:0016020],
aminoacyl-tRNA synthetase multienzyme complex [GO:0017101],
extracellular region [GO:0005576],
cytoplasm [GO:0005737],