AIM2

absent in melanoma 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

GO terms:

Biological Process:
activation of innate immune response [GO:0002218],
positive regulation of defense response to virus by host [GO:0002230],
apoptotic process [GO:0006915],
inflammatory response [GO:0006954],
immune response [GO:0006955],
negative regulation of NF-kappaB transcription factor activity [GO:0032088],
positive regulation of interleukin-1 beta production [GO:0032731],
tumor necrosis factor-mediated signaling pathway [GO:0033209],
cellular response to interferon-beta [GO:0035458],
cellular response to drug [GO:0035690],
NLRP3 inflammasome complex assembly [GO:0044546],
innate immune response [GO:0045087],
interleukin-1 beta secretion [GO:0050702],
positive regulation of interleukin-1 beta secretion [GO:0050718],
positive regulation of NF-kappaB transcription factor activity [GO:0051092],
pyroptosis [GO:0070269],
pyroptosome complex assembly [GO:1904270],
positive regulation of cysteine-type endopeptidase activity [GO:2001056],
immune system process [GO:0002376],

Molecular Function:
double-stranded DNA binding [GO:0003690],
protein binding [GO:0005515],
identical protein binding [GO:0042802],
DNA binding [GO:0003677],

Cellular Component:
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],
mitochondrion [GO:0005739],
cytosol [GO:0005829],
AIM2 inflammasome complex [GO:0097169],
nucleus [GO:0005634],