AIFM2

apoptosis inducing factor mitochondria associated 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
ubiquinone metabolic process [GO:0006743],
apoptotic mitochondrial changes [GO:0008637],
positive regulation of apoptotic process [GO:0043065],
oxidation-reduction process [GO:0055114],
regulation of cellular response to oxidative stress [GO:1900407],
respiratory electron transport chain [GO:0022904],
regulation of apoptotic process [GO:0042981],

Molecular Function:
DNA binding [GO:0003677],
electron-transferring-flavoprotein dehydrogenase activity [GO:0004174],
protein binding [GO:0005515],
oxidoreductase activity [GO:0016491],
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655],
flavin adenine dinucleotide binding [GO:0050660],

Cellular Component:
nucleus [GO:0005634],
cytoplasm [GO:0005737],
mitochondrion [GO:0005739],
mitochondrial outer membrane [GO:0005741],
lipid particle [GO:0005811],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
membrane [GO:0016020],
integral component of membrane [GO:0016021],
mitochondrial membrane [GO:0031966],
extracellular space [GO:0005615],