Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
33296652 heart heart Human NO

GO terms:

Biological Process:
muscle contraction [GO:0006936],
cytoskeleton organization [GO:0007010],
regulation of heart contraction [GO:0008016],
muscle filament sliding [GO:0030049],
intermediate filament organization [GO:0045109],
muscle organ development [GO:0007517],

Molecular Function:
structural constituent of cytoskeleton [GO:0005200],
protein binding [GO:0005515],
cytoskeletal protein binding [GO:0008092],
identical protein binding [GO:0042802],

Cellular Component:
nucleus [GO:0005634],
cytosol [GO:0005829],
intermediate filament [GO:0005882],
fascia adherens [GO:0005916],
intercalated disc [GO:0014704],
Z disc [GO:0030018],
neuromuscular junction [GO:0031594],
sarcolemma [GO:0042383],
intermediate filament cytoskeleton [GO:0045111],
extracellular exosome [GO:0070062],
cardiac myofibril [GO:0097512],
cytoplasm [GO:0005737],
cytoskeleton [GO:0005856],
plasma membrane [GO:0005886],
cell-cell junction [GO:0005911],
gap junction [GO:0005921],
membrane [GO:0016020],
contractile fiber [GO:0043292],
type III intermediate filament [GO:0045098],