Abelson helper integration site 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
morphogenesis of a polarized epithelium [GO:0001738],
heart looping [GO:0001947],
positive regulation of receptor internalization [GO:0002092],
vesicle targeting [GO:0006903],
transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169],
multicellular organism development [GO:0007275],
central nervous system development [GO:0007417],
positive regulation of gene expression [GO:0010628],
retina layer formation [GO:0010842],
positive regulation of neuron projection development [GO:0010976],
vesicle-mediated transport [GO:0016192],
cell projection organization [GO:0030030],
cell differentiation [GO:0030154],
positive regulation of polarized epithelial cell differentiation [GO:0030862],
hindbrain development [GO:0030902],
protein localization to organelle [GO:0033365],
cellular protein localization [GO:0034613],
cloaca development [GO:0035844],
photoreceptor cell outer segment organization [GO:0035845],
pronephric nephron tubule morphogenesis [GO:0039008],
eye photoreceptor cell development [GO:0042462],
negative regulation of apoptotic process [GO:0043066],
positive regulation of growth [GO:0045927],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],
negative regulation of glucose import [GO:0046325],
retinal rod cell development [GO:0046548],
retinal cone cell development [GO:0046549],
regulation of protein secretion [GO:0050708],
regulation of behavior [GO:0050795],
retina development in camera-type eye [GO:0060041],
cilium assembly [GO:0060271],
specification of axis polarity [GO:0065001],
otic vesicle development [GO:0071599],
non-motile cilium assembly [GO:1905515],
pronephric duct morphogenesis [GO:0039023],
Kupffer's vesicle development [GO:0070121],
left/right axis specification [GO:0070986],
ciliary basal body docking [GO:0097711],

Molecular Function:
protein binding [GO:0005515],
identical protein binding [GO:0042802],

Cellular Component:
photoreceptor outer segment [GO:0001750],
cytoplasm [GO:0005737],
centrosome [GO:0005813],
centriole [GO:0005814],
cytoskeleton [GO:0005856],
cell-cell junction [GO:0005911],
adherens junction [GO:0005912],
cilium [GO:0005929],
cell junction [GO:0030054],
MKS complex [GO:0036038],
ciliary basal body [GO:0036064],
cell projection [GO:0042995],
non-motile cilium [GO:0097730],
cytosol [GO:0005829],