Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Li Fraumeni Human YES
31945054 IMR-90 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
28459194 HepG2 Human NO

GO terms:

Biological Process:
sulfur amino acid metabolic process [GO:0000096],
response to hypoxia [GO:0001666],
chronic inflammatory response to antigenic stimulus [GO:0002439],
one-carbon metabolic process [GO:0006730],
response to nutrient [GO:0007584],
S-adenosylhomocysteine catabolic process [GO:0019510],
methylation [GO:0032259],
S-adenosylmethionine cycle [GO:0033353],
circadian sleep/wake cycle [GO:0042745],

Molecular Function:
adenosylhomocysteinase activity [GO:0004013],
protein binding [GO:0005515],
adenyl nucleotide binding [GO:0030554],
identical protein binding [GO:0042802],
NAD binding [GO:0051287],
copper ion binding [GO:0005507],
protein self-association [GO:0043621],

Cellular Component:
nucleus [GO:0005634],
cytosol [GO:0005829],
melanosome [GO:0042470],
neuron projection [GO:0043005],
extracellular exosome [GO:0070062],