DCK

deoxycytidine kinase

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
dAMP biosynthetic process [GO:0006170],
pyrimidine nucleotide metabolic process [GO:0006220],
phosphorylation [GO:0016310],
pyrimidine nucleoside salvage [GO:0043097],
purine-containing compound salvage [GO:0043101],
nucleobase-containing compound metabolic process [GO:0006139],
drug metabolic process [GO:0017144],
deoxycytidine metabolic process [GO:0046092],

Molecular Function:
deoxyadenosine kinase activity [GO:0004136],
deoxycytidine kinase activity [GO:0004137],
deoxyguanosine kinase activity [GO:0004138],
ATP binding [GO:0005524],
drug binding [GO:0008144],
deoxynucleoside kinase activity [GO:0019136],
protein homodimerization activity [GO:0042803],
nucleotide binding [GO:0000166],
magnesium ion binding [GO:0000287],
kinase activity [GO:0016301],
transferase activity [GO:0016740],
nucleoside kinase activity [GO:0019206],
pyrimidine deoxyribonucleoside binding [GO:0032548],

Cellular Component:
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],
mitochondrion [GO:0005739],
cytosol [GO:0005829],
nucleus [GO:0005634],