DBNL

drebrin like

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
adaptive immune response [GO:0002250],
immune system process [GO:0002376],
endocytosis [GO:0006897],
receptor-mediated endocytosis [GO:0006898],
synapse assembly [GO:0007416],
Rac protein signal transduction [GO:0016601],
regulation of actin filament polymerization [GO:0030833],
positive regulation of axon extension [GO:0045773],
neuron projection morphogenesis [GO:0048812],
actin filament severing [GO:0051014],
barbed-end actin filament capping [GO:0051016],
actin filament bundle assembly [GO:0051017],
positive regulation of dendritic spine morphogenesis [GO:0061003],
podosome assembly [GO:0071800],
ruffle assembly [GO:0097178],
postsynaptic actin cytoskeleton organization [GO:0098974],
activation of JUN kinase activity [GO:0007257],
neutrophil degranulation [GO:0043312],

Molecular Function:
actin binding [GO:0003779],
protein binding [GO:0005515],
protein C-terminus binding [GO:0008022],
protein domain specific binding [GO:0019904],
actin filament binding [GO:0051015],
enzyme activator activity [GO:0008047],
cadherin binding [GO:0045296],

Cellular Component:
ruffle [GO:0001726],
podosome [GO:0002102],
intracellular [GO:0005622],
cytoplasm [GO:0005737],
endosome [GO:0005768],
Golgi apparatus [GO:0005794],
cytoskeleton [GO:0005856],
actin filament [GO:0005884],
plasma membrane [GO:0005886],
cell cortex [GO:0005938],
postsynaptic density [GO:0014069],
membrane [GO:0016020],
lamellipodium [GO:0030027],
cell junction [GO:0030054],
dendrite [GO:0030425],
site of polarized growth [GO:0030427],
cortical actin cytoskeleton [GO:0030864],
cytoplasmic vesicle [GO:0031410],
cell projection [GO:0042995],
synapse [GO:0045202],
postsynaptic membrane [GO:0045211],
Golgi membrane [GO:0000139],
extracellular region [GO:0005576],
early endosome [GO:0005769],
cytosol [GO:0005829],
clathrin-coated vesicle membrane [GO:0030665],
secretory granule lumen [GO:0034774],
perikaryon [GO:0043204],
extracellular exosome [GO:0070062],
tertiary granule lumen [GO:1904724],
ficolin-1-rich granule lumen [GO:1904813],