DAG1

dystroglycan 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
positive regulation of cell-matrix adhesion [GO:0001954],
morphogenesis of an epithelium [GO:0002009],
morphogenesis of an epithelial sheet [GO:0002011],
membrane protein ectodomain proteolysis [GO:0006509],
axon guidance [GO:0007411],
aging [GO:0007568],
regulation of gastrulation [GO:0010470],
regulation of epithelial to mesenchymal transition [GO:0010717],
response to denervation involved in regulation of muscle adaptation [GO:0014894],
muscle attachment [GO:0016203],
calcium-dependent cell-matrix adhesion [GO:0016340],
regulation of embryonic cell shape [GO:0016476],
modulation by virus of host morphology or physiology [GO:0019048],
nerve development [GO:0021675],
nerve maturation [GO:0021682],
myelination in peripheral nervous system [GO:0022011],
extracellular matrix organization [GO:0030198],
negative regulation of cell migration [GO:0030336],
axon regeneration [GO:0031103],
positive regulation of myelination [GO:0031643],
microtubule anchoring [GO:0034453],
skeletal muscle tissue regeneration [GO:0043403],
negative regulation of MAPK cascade [GO:0043409],
response to peptide hormone [GO:0043434],
positive regulation of protein kinase activity [GO:0045860],
viral entry into host cell [GO:0046718],
positive regulation of oligodendrocyte differentiation [GO:0048714],
regulation of synapse organization [GO:0050807],
negative regulation of protein kinase B signaling [GO:0051898],
angiogenesis involved in wound healing [GO:0060055],
epithelial tube branching involved in lung morphogenesis [GO:0060441],
branching involved in salivary gland morphogenesis [GO:0060445],
cellular response to mechanical stimulus [GO:0071260],
cellular response to cholesterol [GO:0071397],
commissural neuron axon guidance [GO:0071679],
basement membrane organization [GO:0071711],
retrograde trans-synaptic signaling by trans-synaptic protein complex [GO:0098942],
positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261],
Schwann cell development [GO:0014044],
viral process [GO:0016032],

Molecular Function:
virus receptor activity [GO:0001618],
dystroglycan binding [GO:0002162],
actin binding [GO:0003779],
calcium ion binding [GO:0005509],
protein binding [GO:0005515],
structural constituent of muscle [GO:0008307],
tubulin binding [GO:0015631],
vinculin binding [GO:0017166],
SH2 domain binding [GO:0042169],
laminin binding [GO:0043236],
laminin-1 binding [GO:0043237],
alpha-actinin binding [GO:0051393],

Cellular Component:
extracellular region [GO:0005576],
basement membrane [GO:0005604],
extracellular space [GO:0005615],
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],
endoplasmic reticulum lumen [GO:0005788],
Golgi lumen [GO:0005796],
cytosol [GO:0005829],
cytoskeleton [GO:0005856],
plasma membrane [GO:0005886],
cell-cell junction [GO:0005911],
focal adhesion [GO:0005925],
external side of plasma membrane [GO:0009897],
basal plasma membrane [GO:0009925],
dystrophin-associated glycoprotein complex [GO:0016010],
dystroglycan complex [GO:0016011],
integral component of membrane [GO:0016021],
basolateral plasma membrane [GO:0016323],
lamellipodium [GO:0030027],
filopodium [GO:0030175],
node of Ranvier [GO:0033268],
nuclear periphery [GO:0034399],
sarcolemma [GO:0042383],
costamere [GO:0043034],
plasma membrane raft [GO:0044853],
postsynaptic membrane [GO:0045211],
extracellular exosome [GO:0070062],
contractile ring [GO:0070938],
glutamatergic synapse [GO:0098978],
GABA-ergic synapse [GO:0098982],
postsynaptic cytosol [GO:0099524],
nucleus [GO:0005634],
adherens junction [GO:0005912],
membrane [GO:0016020],
cell junction [GO:0030054],
membrane raft [GO:0045121],
synapse [GO:0045202],