CYB5R3

cytochrome b5 reductase 3

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES
31945125 Primary astrocytes derived from brain Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31983656 MSC Human YES

GO terms:

Biological Process:
cholesterol biosynthetic process [GO:0006695],
xenobiotic metabolic process [GO:0006805],
blood circulation [GO:0008015],
L-ascorbic acid metabolic process [GO:0019852],
neutrophil degranulation [GO:0043312],
oxidation-reduction process [GO:0055114],
lipid metabolic process [GO:0006629],
steroid biosynthetic process [GO:0006694],
steroid metabolic process [GO:0008202],
cholesterol metabolic process [GO:0008203],
sterol biosynthetic process [GO:0016126],

Molecular Function:
cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128],
protein binding [GO:0005515],
AMP binding [GO:0016208],
ADP binding [GO:0043531],
NAD binding [GO:0051287],
FAD binding [GO:0071949],
oxidoreductase activity [GO:0016491],
flavin adenine dinucleotide binding [GO:0050660],

Cellular Component:
extracellular region [GO:0005576],
cytoplasm [GO:0005737],
mitochondrion [GO:0005739],
mitochondrial outer membrane [GO:0005741],
endoplasmic reticulum [GO:0005783],
endoplasmic reticulum membrane [GO:0005789],
lipid particle [GO:0005811],
hemoglobin complex [GO:0005833],
membrane [GO:0016020],
azurophil granule lumen [GO:0035578],
mitochondrial inner membrane [GO:0005743],