CXCL6

C-X-C motif chemokine ligand 6

Link to human ortholog


Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
30626320 HBEC Human NO
30801661 HDF Human NO
30988157 IMR-90 Human YES
31183403 IMR-90 Human YES
31242426 HFF-2  Human YES
31543366 WA09 Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
leukocyte homeostasis [GO:0001776],
chemotaxis [GO:0006935],
inflammatory response [GO:0006954],
immune response [GO:0006955],
signal transduction [GO:0007165],
G-protein coupled receptor signaling pathway [GO:0007186],
cell-cell signaling [GO:0007267],
neutrophil chemotaxis [GO:0030593],
leukocyte chemotaxis [GO:0030595],
regulation of chemokine production [GO:0032642],
neutrophil activation [GO:0042119],
defense response to bacterium [GO:0042742],
chemokine-mediated signaling pathway [GO:0070098],
regulation of neutrophil mediated killing of gram-negative bacterium [GO:0070951],
cellular response to lipopolysaccharide [GO:0071222],

Molecular Function:
protein binding [GO:0005515],
chemokine activity [GO:0008009],
heparin binding [GO:0008201],
CXCR chemokine receptor binding [GO:0045236],

Cellular Component:
extracellular region [GO:0005576],
extracellular space [GO:0005615],