CXCL13

C-X-C motif chemokine ligand 13

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31184599 WI-38 YES
32023351 Primary bone cells derived from bone marrow Mouse NO

GO terms:

Biological Process:
germinal center formation [GO:0002467],
lymphocyte chemotaxis across high endothelial venule [GO:0002518],
chronic inflammatory response [GO:0002544],
regulation of humoral immune response [GO:0002920],
inflammatory response [GO:0006954],
immune response [GO:0006955],
cell surface receptor signaling pathway [GO:0007166],
G-protein coupled receptor signaling pathway [GO:0007186],
positive regulation of cytosolic calcium ion concentration [GO:0007204],
cell-cell signaling [GO:0007267],
positive regulation of T cell chemotaxis [GO:0010820],
neutrophil chemotaxis [GO:0030593],
leukocyte chemotaxis [GO:0030595],
positive regulation of integrin activation [GO:0033625],
positive regulation of cell-cell adhesion mediated by integrin [GO:0033634],
B cell chemotaxis [GO:0035754],
endothelial cell chemotaxis to fibroblast growth factor [GO:0035768],
defense response to bacterium [GO:0042742],
regulation of angiogenesis [GO:0045765],
chemokine-mediated signaling pathway [GO:0070098],
cellular response to lipopolysaccharide [GO:0071222],
activation of GTPase activity [GO:0090630],
negative regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000545],
chemotaxis [GO:0006935],
defense response [GO:0006952],
killing of cells of other organism [GO:0031640],
B cell chemotaxis across high endothelial venule [GO:0035769],
lymph node development [GO:0048535],

Molecular Function:
chemokine activity [GO:0008009],
heparin binding [GO:0008201],
fibroblast growth factor binding [GO:0017134],
CXCR5 chemokine receptor binding [GO:0031724],
CCR10 chemokine receptor binding [GO:0031735],
CXCR chemokine receptor binding [GO:0045236],
receptor agonist activity [GO:0048018],
CXCR3 chemokine receptor binding [GO:0048248],
cytokine activity [GO:0005125],

Cellular Component:
extracellular region [GO:0005576],
extracellular space [GO:0005615],