AFP

alpha fetoprotein

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
30988157 IMR-90 Human YES

GO terms:

Biological Process:
ovulation from ovarian follicle [GO:0001542],
transport [GO:0006810],
progesterone metabolic process [GO:0042448],
post-translational protein modification [GO:0043687],
cellular protein metabolic process [GO:0044267],
SMAD protein signal transduction [GO:0060395],
sexual reproduction [GO:0019953],

Molecular Function:
fatty acid binding [GO:0005504],
protein binding [GO:0005515],
zinc ion binding [GO:0008270],
beta-glucuronidase activity [GO:0004566],
metal ion binding [GO:0046872],

Cellular Component:
extracellular space [GO:0005615],
cytoplasm [GO:0005737],
endoplasmic reticulum lumen [GO:0005788],
extracellular region [GO:0005576],