AFF3

AF4/FMR2 family member 3

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

GO terms:

Biological Process:
regulation of gene expression [GO:0010468],
response to tumor necrosis factor [GO:0034612],
embryonic hindlimb morphogenesis [GO:0035116],
transcription, DNA-templated [GO:0006351],
regulation of transcription, DNA-templated [GO:0006355],

Molecular Function:
double-stranded DNA binding [GO:0003690],
DNA binding [GO:0003677],
transcription factor activity, sequence-specific DNA binding [GO:0003700],

Cellular Component:
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
cytosol [GO:0005829],
transcription elongation factor complex [GO:0008023],
nuclear body [GO:0016604],
ELL-EAF complex [GO:0032783],