casein kinase 1 alpha 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
21331045 Colon Human NO
31945054 IMR-90 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 Skin, Lung Human YES
 23324396 hTERT RPE-1 Human NO

GO terms:

Biological Process:
cell morphogenesis [GO:0000902],
protein phosphorylation [GO:0006468],
Golgi organization [GO:0007030],
cell cycle [GO:0007049],
signal transduction [GO:0007165],
cell surface receptor signaling pathway [GO:0007166],
Wnt signaling pathway [GO:0016055],
peptidyl-serine phosphorylation [GO:0018105],
positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436],
intermediate filament cytoskeleton organization [GO:0045104],
cell division [GO:0051301],
negative regulation of canonical Wnt signaling pathway [GO:0090090],
regulation of GTP binding [GO:1904424],
beta-catenin destruction complex assembly [GO:1904885],
beta-catenin destruction complex disassembly [GO:1904886],
phosphorylation [GO:0016310],

Molecular Function:
protein kinase activity [GO:0004672],
protein serine/threonine kinase activity [GO:0004674],
protein binding [GO:0005515],
ATP binding [GO:0005524],
kinase activity [GO:0016301],
nucleotide binding [GO:0000166],
magnesium ion binding [GO:0000287],
transferase activity [GO:0016740],
peptide binding [GO:0042277],
phosphoprotein binding [GO:0051219],

Cellular Component:
condensed chromosome kinetochore [GO:0000777],
nucleus [GO:0005634],
cytoplasm [GO:0005737],
centrosome [GO:0005813],
cytosol [GO:0005829],
mRNA cleavage and polyadenylation specificity factor complex [GO:0005847],
cilium [GO:0005929],
membrane [GO:0016020],
nuclear speck [GO:0016607],
beta-catenin destruction complex [GO:0030877],
ciliary basal body [GO:0036064],
keratin filament [GO:0045095],
ribonucleoprotein complex [GO:1990904],
chromosome, centromeric region [GO:0000775],
kinetochore [GO:0000776],
chromosome [GO:0005694],
cytoskeleton [GO:0005856],
cell projection [GO:0042995],