AF4/FMR2 family member 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES
31945125 Primary astrocytes derived from brain Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
33296652 heart heart Human NO

GO terms:

Biological Process:
regulation of transcription, DNA-templated [GO:0006355],
regulation of gene expression [GO:0010468],
transcription, DNA-templated [GO:0006351],
positive regulation of transcription, DNA-templated [GO:0045893],

Molecular Function:
transcription factor activity, sequence-specific DNA binding [GO:0003700],
protein binding [GO:0005515],

Cellular Component:
nucleus [GO:0005634],
transcription elongation factor complex [GO:0008023],
ELL-EAF complex [GO:0032783],