AFAP1L2
actin filament associated protein 1 like 2
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 29548335 | Saos-2 | Human | YES | |
GO terms:
Biological Process:
inflammatory response [GO:0006954],
regulation of mitotic cell cycle [GO:0007346],
regulation of interleukin-6 production [GO:0032675],
positive regulation of interleukin-8 production [GO:0032757],
positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742],
positive regulation of transcription, DNA-templated [GO:0045893],
positive regulation of protein tyrosine kinase activity [GO:0061098],
regulation of signal transduction [GO:0009966],
Molecular Function:
SH3 domain binding [GO:0017124],
protein tyrosine kinase activator activity [GO:0030296],
signaling adaptor activity [GO:0035591],
SH2 domain binding [GO:0042169],
protein binding [GO:0005515],
Cellular Component:
cytoplasm [GO:0005737],
cytosol [GO:0005829],
plasma membrane [GO:0005886],