actin filament associated protein 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
regulation of signal transduction [GO:0009966],
regulation of cytoskeleton organization [GO:0051493],

Molecular Function:
actin binding [GO:0003779],
SH3 domain binding [GO:0017124],
SH2 domain binding [GO:0042169],

Cellular Component:
cytosol [GO:0005829],
focal adhesion [GO:0005925],
actin cytoskeleton [GO:0015629],
cytoplasm [GO:0005737],
cytoskeleton [GO:0005856],
actin filament [GO:0005884],