ADTRP
androgen dependent TFPI regulating protein
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 28844647 | BJ, WI-38, IMR-90, MRC-5, HFF, HCA258 | Skin, Lung | Human | YES |
| 29548335 | Saos-2 | Human | YES | |
| 30988157 | IMR-90 | Human | YES | |
Status in senescence: Down-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 29321003 | Primary bronchial epithelial cells derived from lung | Human | YES | |
GO terms:
Biological Process:
positive regulation of protein phosphorylation [GO:0001934],
cell migration involved in sprouting angiogenesis [GO:0002042],
negative regulation of leukocyte migration [GO:0002686],
negative regulation of extracellular matrix constituent secretion [GO:0003332],
positive regulation of gene expression [GO:0010628],
negative regulation of blood coagulation [GO:0030195],
long-chain fatty acid catabolic process [GO:0042758],
protein kinase B signaling [GO:0043491],
negative regulation of protein secretion [GO:0050709],
cellular response to steroid hormone stimulus [GO:0071383],
negative regulation of leukocyte cell-cell adhesion [GO:1903038],
negative regulation of lymphocyte migration [GO:2000402],
lipid metabolic process [GO:0006629],
Molecular Function:
hydrolase activity [GO:0016787],
Cellular Component:
caveola [GO:0005901],
cell surface [GO:0009986],
membrane [GO:0016020],
integral component of membrane [GO:0016021],
plasma membrane [GO:0005886],