CPZ

carboxypeptidase Z

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
proteolysis [GO:0006508],
peptide metabolic process [GO:0006518],
Wnt signaling pathway [GO:0016055],
protein processing [GO:0016485],

Molecular Function:
metallocarboxypeptidase activity [GO:0004181],
zinc ion binding [GO:0008270],
carboxypeptidase activity [GO:0004180],
peptidase activity [GO:0008233],
metallopeptidase activity [GO:0008237],
hydrolase activity [GO:0016787],
metal ion binding [GO:0046872],

Cellular Component:
extracellular space [GO:0005615],
extracellular region [GO:0005576],
extracellular matrix [GO:0031012],