CPM

carboxypeptidase M

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 Skin, Lung Human YES
29321003 Primary bronchial epithelial cells derived from lung Human YES
29548335 Li Fraumeni Human YES
30977188 MSC Human YES

GO terms:

Biological Process:
peptide metabolic process [GO:0006518],
anatomical structure morphogenesis [GO:0009653],
protein processing [GO:0016485],
proteolysis [GO:0006508],

Molecular Function:
carboxypeptidase activity [GO:0004180],
metallocarboxypeptidase activity [GO:0004181],
zinc ion binding [GO:0008270],
peptidase activity [GO:0008233],
metallopeptidase activity [GO:0008237],
hydrolase activity [GO:0016787],
metal ion binding [GO:0046872],

Cellular Component:
extracellular region [GO:0005576],
extracellular space [GO:0005615],
plasma membrane [GO:0005886],
cell surface [GO:0009986],
anchored component of membrane [GO:0031225],
extracellular exosome [GO:0070062],
membrane [GO:0016020],