ADRB2

adrenoceptor beta 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
diet induced thermogenesis [GO:0002024],
vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure [GO:0002025],
regulation of sodium ion transport [GO:0002028],
desensitization of G-protein coupled receptor protein signaling pathway by arrestin [GO:0002032],
receptor-mediated endocytosis [GO:0006898],
cell surface receptor signaling pathway [GO:0007166],
activation of transmembrane receptor protein tyrosine kinase activity [GO:0007171],
G-protein coupled receptor signaling pathway [GO:0007186],
adenylate cyclase-modulating G-protein coupled receptor signaling pathway [GO:0007188],
activation of adenylate cyclase activity [GO:0007190],
endosome to lysosome transport [GO:0008333],
response to cold [GO:0009409],
positive regulation of protein kinase A signaling [GO:0010739],
protein deubiquitination [GO:0016579],
positive regulation of bone mineralization [GO:0030501],
positive regulation of protein ubiquitination [GO:0031398],
heat generation [GO:0031649],
negative regulation of multicellular organism growth [GO:0040015],
positive regulation of MAPK cascade [GO:0043410],
bone resorption [GO:0045453],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],
negative regulation of smooth muscle contraction [GO:0045986],
brown fat cell differentiation [GO:0050873],
membrane organization [GO:0061024],
adrenergic receptor signaling pathway [GO:0071875],
adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880],
positive regulation of protein serine/threonine kinase activity [GO:0071902],
positive regulation of autophagosome maturation [GO:1901098],
positive regulation of lipophagy [GO:1904504],
cellular response to beta-amyloid [GO:1904646],
response to psychosocial stress [GO:1990911],
positive regulation of cAMP-dependent protein kinase activity [GO:2000481],
positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [GO:2000969],
regulation of systemic arterial blood pressure by norepinephrine-epinephrine [GO:0001993],
diaphragm contraction [GO:0002086],
positive regulation of the force of heart contraction by epinephrine [GO:0003059],
regulation of smooth muscle contraction [GO:0006940],
signal transduction [GO:0007165],
adenylate cyclase-activating G-protein coupled receptor signaling pathway [GO:0007189],
positive regulation of cell proliferation [GO:0008284],
associative learning [GO:0008306],
positive regulation of sodium ion transport [GO:0010765],
negative regulation of angiogenesis [GO:0016525],
negative regulation of ossification [GO:0030279],
positive regulation of ATPase activity [GO:0032781],
synaptic transmission, glutamatergic [GO:0035249],
negative regulation of urine volume [GO:0035811],
wound healing [GO:0042060],
positive regulation of apoptotic process [GO:0043065],
positive regulation of potassium ion transport [GO:0043268],
positive regulation of heart contraction [GO:0045823],
positive regulation of skeletal muscle tissue growth [GO:0048633],
negative regulation of inflammatory response [GO:0050728],
regulation of calcium ion transport [GO:0051924],
regulation of sensory perception of pain [GO:0051930],
excitatory postsynaptic potential [GO:0060079],
cellular response to hypoxia [GO:0071456],
negative regulation of platelet aggregation [GO:0090331],
regulation of synaptic vesicle exocytosis [GO:2000300],

Molecular Function:
beta-amyloid binding [GO:0001540],
G-protein coupled receptor activity [GO:0004930],
beta2-adrenergic receptor activity [GO:0004941],
protein binding [GO:0005515],
adenylate cyclase binding [GO:0008179],
potassium channel regulator activity [GO:0015459],
identical protein binding [GO:0042802],
protein homodimerization activity [GO:0042803],
macromolecular complex binding [GO:0044877],
epinephrine binding [GO:0051379],
norepinephrine binding [GO:0051380],
G-protein alpha-subunit binding [GO:0001965],
adrenergic receptor activity [GO:0004935],
drug binding [GO:0008144],
enzyme binding [GO:0019899],
B2 bradykinin receptor binding [GO:0031713],
dopamine binding [GO:0035240],
ionotropic glutamate receptor binding [GO:0035255],
protein phosphatase 2A binding [GO:0051721],

Cellular Component:
nucleus [GO:0005634],
lysosome [GO:0005764],
endosome [GO:0005768],
early endosome [GO:0005769],
plasma membrane [GO:0005886],
integral component of plasma membrane [GO:0005887],
endosome membrane [GO:0010008],
membrane [GO:0016020],
apical plasma membrane [GO:0016324],
clathrin-coated vesicle membrane [GO:0030665],
receptor complex [GO:0043235],
cytoplasm [GO:0005737],
caveola [GO:0005901],
integral component of membrane [GO:0016021],
axon [GO:0030424],
dendrite [GO:0030425],
neuronal cell body membrane [GO:0032809],
sarcolemma [GO:0042383],
dendritic spine [GO:0043197],
intracellular membrane-bounded organelle [GO:0043231],
glutamatergic synapse [GO:0098978],