CORO1B

coronin 1B

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES
31983656 MSC Human YES

GO terms:

Biological Process:
actin filament organization [GO:0007015],
cell migration [GO:0016477],
actin cytoskeleton organization [GO:0030036],
ruffle organization [GO:0031529],
negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316],
endothelial cell chemotaxis [GO:0035767],
cellular response to platelet-derived growth factor stimulus [GO:0036120],
wound healing [GO:0042060],
actin filament bundle assembly [GO:0051017],
protein kinase C signaling [GO:0070528],
negative regulation of smooth muscle cell chemotaxis [GO:0071672],
actin filament branching [GO:0090135],
protein localization to cell leading edge [GO:1902463],
negative regulation of lamellipodium morphogenesis [GO:2000393],
positive regulation of lamellipodium morphogenesis [GO:2000394],
regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315],

Molecular Function:
actin binding [GO:0003779],
protein binding [GO:0005515],
cytoskeletal protein binding [GO:0008092],
identical protein binding [GO:0042802],
macromolecular complex binding [GO:0044877],
actin filament binding [GO:0051015],
Arp2/3 complex binding [GO:0071933],
cadherin binding [GO:0045296],

Cellular Component:
stress fiber [GO:0001725],
cytoplasm [GO:0005737],
cytosol [GO:0005829],
cytoskeleton [GO:0005856],
actin filament [GO:0005884],
plasma membrane [GO:0005886],
lamellipodium [GO:0030027],
cell leading edge [GO:0031252],
perinuclear region of cytoplasm [GO:0048471],
cell periphery [GO:0071944],
focal adhesion [GO:0005925],
extracellular exosome [GO:0070062],