CORO1A

coronin 1A

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
immunological synapse formation [GO:0001771],
phagolysosome assembly [GO:0001845],
calcium ion transport [GO:0006816],
phagocytosis [GO:0006909],
actin filament organization [GO:0007015],
regulation of cell shape [GO:0008360],
cell migration [GO:0016477],
actin cytoskeleton organization [GO:0030036],
positive regulation of cell migration [GO:0030335],
leukocyte chemotaxis [GO:0030595],
negative regulation of vesicle fusion [GO:0031339],
cell-substrate adhesion [GO:0031589],
uropod organization [GO:0032796],
regulation of actin cytoskeleton organization [GO:0032956],
nerve growth factor signaling pathway [GO:0038180],
positive regulation of T cell proliferation [GO:0042102],
T cell homeostasis [GO:0043029],
natural killer cell degranulation [GO:0043320],
negative regulation of neuron apoptotic process [GO:0043524],
innate immune response [GO:0045087],
homeostasis of number of cells within a tissue [GO:0048873],
positive chemotaxis [GO:0050918],
negative regulation of actin nucleation [GO:0051126],
regulation of release of sequestered calcium ion into cytosol [GO:0051279],
early endosome to recycling endosome transport [GO:0061502],
cellular response to interleukin-4 [GO:0071353],
regulation of actin polymerization or depolymerization [GO:0008064],
regulation of actin filament polymerization [GO:0030833],
response to cytokine [GO:0034097],
positive regulation of T cell activation [GO:0050870],

Molecular Function:
RNA binding [GO:0003723],
actin binding [GO:0003779],
actin monomer binding [GO:0003785],
protein binding [GO:0005515],
protein C-terminus binding [GO:0008022],
cytoskeletal protein binding [GO:0008092],
myosin heavy chain binding [GO:0032036],
protein homodimerization activity [GO:0042803],
phosphatidylinositol 3-kinase binding [GO:0043548],
actin filament binding [GO:0051015],
identical protein binding [GO:0042802],

Cellular Component:
immunological synapse [GO:0001772],
phagocytic cup [GO:0001891],
nucleus [GO:0005634],
cytoplasm [GO:0005737],
early endosome [GO:0005769],
cytosol [GO:0005829],
actin filament [GO:0005884],
plasma membrane [GO:0005886],
cell-cell junction [GO:0005911],
membrane [GO:0016020],
lamellipodium [GO:0030027],
axon [GO:0030424],
phagocytic vesicle membrane [GO:0030670],
cortical actin cytoskeleton [GO:0030864],
macromolecular complex [GO:0032991],
phagocytic vesicle [GO:0045335],
extracellular exosome [GO:0070062],
glutamatergic synapse [GO:0098978],
cytoskeleton [GO:0005856],
actin cytoskeleton [GO:0015629],
cell leading edge [GO:0031252],
cytoplasmic vesicle [GO:0031410],
stereocilium tip [GO:0032426],
synapse [GO:0045202],