ADRA1B

adrenoceptor alpha 1B

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996],
G-protein coupled receptor signaling pathway [GO:0007186],
phospholipase C-activating G-protein coupled receptor signaling pathway [GO:0007200],
positive regulation of cytosolic calcium ion concentration [GO:0007204],
cell-cell signaling [GO:0007267],
intracellular signal transduction [GO:0035556],
positive regulation of MAPK cascade [GO:0043410],
positive regulation of vasoconstriction [GO:0045907],
regulation of cardiac muscle contraction [GO:0055117],
adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880],
blood vessel remodeling [GO:0001974],
response to amphetamine [GO:0001975],
vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure [GO:0001987],
positive regulation of the force of heart contraction by epinephrine-norepinephrine [GO:0001997],
regulation of muscle contraction [GO:0006937],
signal transduction [GO:0007165],
adult heart development [GO:0007512],
locomotory behavior [GO:0007626],
visual learning [GO:0008542],
response to hormone [GO:0009725],
regulation of vasoconstriction [GO:0019229],
negative regulation of Rho protein signal transduction [GO:0035024],
organ growth [GO:0035265],
glucose homeostasis [GO:0042593],
response to morphine [GO:0043278],
negative regulation of glycogen catabolic process [GO:0045818],
positive regulation of glycogen catabolic process [GO:0045819],
behavioral response to cocaine [GO:0048148],
response to steroid hormone [GO:0048545],
cell growth involved in cardiac muscle cell development [GO:0061049],

Molecular Function:
G-protein coupled receptor activity [GO:0004930],
alpha1-adrenergic receptor activity [GO:0004937],
protein binding [GO:0005515],
protein heterodimerization activity [GO:0046982],
adrenergic receptor activity [GO:0004935],

Cellular Component:
nucleus [GO:0005634],
cytoplasm [GO:0005737],
plasma membrane [GO:0005886],
integral component of plasma membrane [GO:0005887],
caveola [GO:0005901],
nuclear membrane [GO:0031965],
intercalated disc [GO:0014704],
membrane [GO:0016020],
integral component of membrane [GO:0016021],
T-tubule [GO:0030315],