ADPRH

ADP-ribosylarginine hydrolase

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2, Li-Fraumeni Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
cellular protein modification process [GO:0006464],
intracellular protein transport [GO:0006886],
protein de-ADP-ribosylation [GO:0051725],
activation of GTPase activity [GO:0090630],
regulation of autophagosome assembly [GO:2000785],

Molecular Function:
magnesium ion binding [GO:0000287],
ADP-ribosylarginine hydrolase activity [GO:0003875],
GTPase activator activity [GO:0005096],
protein binding [GO:0005515],
Rab GTPase binding [GO:0017137],
potassium ion binding [GO:0030955],
hydrolase activity [GO:0016787],
metal ion binding [GO:0046872],

Cellular Component:
extracellular space [GO:0005615],
autophagosome [GO:0005776],
cytosol [GO:0005829],
recycling endosome [GO:0055037],