COL6A3

collagen type VI alpha 3 chain

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Li Fraumeni Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
cell adhesion [GO:0007155],
muscle organ development [GO:0007517],
negative regulation of endopeptidase activity [GO:0010951],
extracellular matrix organization [GO:0030198],

Molecular Function:
serine-type endopeptidase inhibitor activity [GO:0004867],
extracellular matrix structural constituent conferring tensile strength [GO:0030020],

Cellular Component:
extracellular region [GO:0005576],
collagen type VI trimer [GO:0005589],
extracellular space [GO:0005615],
endoplasmic reticulum lumen [GO:0005788],
extracellular matrix [GO:0031012],
sarcolemma [GO:0042383],
extracellular exosome [GO:0070062],
extracellular vesicle [GO:1903561],
collagen trimer [GO:0005581],