COL6A1

collagen type VI alpha 1 chain

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
31945054 IMR-90 Human YES
31945125 Primary astrocytes derived from brain Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
32029712 Primary synovial fibroblast Human YES

GO terms:

Biological Process:
osteoblast differentiation [GO:0001649],
cell adhesion [GO:0007155],
extracellular matrix organization [GO:0030198],
endodermal cell differentiation [GO:0035987],
cellular response to amino acid stimulus [GO:0071230],

Molecular Function:
collagen binding [GO:0005518],
extracellular matrix structural constituent conferring tensile strength [GO:0030020],
platelet-derived growth factor binding [GO:0048407],

Cellular Component:
extracellular region [GO:0005576],
collagen type VI trimer [GO:0005589],
extracellular space [GO:0005615],
lysosomal membrane [GO:0005765],
endoplasmic reticulum lumen [GO:0005788],
membrane [GO:0016020],
macromolecular complex [GO:0032991],
sarcolemma [GO:0042383],
extracellular exosome [GO:0070062],
collagen trimer [GO:0005581],
extracellular matrix [GO:0031012],