ADNP homeobox 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
regulation of transcription from RNA polymerase II promoter [GO:0006357],
neuron differentiation [GO:0030182],
positive regulation of cell growth [GO:0030307],
cellular response to oxidative stress [GO:0034599],
negative regulation of cell death [GO:0060548],
cellular response to retinoic acid [GO:0071300],

Molecular Function:
RNA polymerase II transcription factor activity, sequence-specific DNA binding [GO:0000981],
molecular_function [GO:0003674],
DNA binding [GO:0003677],
protein binding [GO:0005515],
metal ion binding [GO:0046872],
nucleic acid binding [GO:0003676],

Cellular Component:
nuclear chromatin [GO:0000790],
cellular_component [GO:0005575],
nucleus [GO:0005634],