activity dependent neuroprotector homeobox

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
short-term memory [GO:0007614],
negative regulation of gene expression [GO:0010629],
regulation of protein ADP-ribosylation [GO:0010835],
positive regulation of neuron projection development [GO:0010976],
cGMP-mediated signaling [GO:0019934],
negative regulation of protein binding [GO:0032091],
activation of protein kinase activity [GO:0032147],
nitric oxide homeostasis [GO:0033484],
negative regulation of neuron apoptotic process [GO:0043524],
positive regulation of axon extension [GO:0045773],
positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731],
negative regulation of synaptic transmission [GO:0050805],
positive regulation of synapse assembly [GO:0051965],
regulation of transcription from RNA polymerase II promoter [GO:0006357],
response to carbohydrate [GO:0009743],
response to inorganic substance [GO:0010035],
cellular response to extracellular stimulus [GO:0031668],
estrous cycle [GO:0044849],

Molecular Function:
nucleic acid binding [GO:0003676],
DNA binding [GO:0003677],
chromatin binding [GO:0003682],
copper ion binding [GO:0005507],
protein binding [GO:0005515],
peptide binding [GO:0042277],
metal ion binding [GO:0046872],
beta-tubulin binding [GO:0048487],
RNA polymerase II transcription factor activity, sequence-specific DNA binding [GO:0000981],

Cellular Component:
extracellular space [GO:0005615],
nucleus [GO:0005634],
cytoplasm [GO:0005737],
axon [GO:0030424],
dendrite [GO:0030425],
neuronal cell body [GO:0043025],
nuclear chromatin [GO:0000790],