ADI1
acireductone dioxygenase 1
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 29321003 | Primary bronchial epithelial cells derived from lung | Human | YES | |
| 29548335 | Saos-2 | Human | YES | |
Status in senescence: Down-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 31945054 | IMR-90 | Human | YES | |
| 31983656 | MSC | Human | YES | |
GO terms:
Biological Process:
methionine metabolic process [GO:0006555],
L-methionine biosynthetic process from methylthioadenosine [GO:0019509],
oxidation-reduction process [GO:0055114],
cellular amino acid biosynthetic process [GO:0008652],
methionine biosynthetic process [GO:0009086],
Molecular Function:
iron ion binding [GO:0005506],
protein binding [GO:0005515],
acireductone dioxygenase [iron(II)-requiring] activity [GO:0010309],
oxidoreductase activity [GO:0016491],
metal ion binding [GO:0046872],
dioxygenase activity [GO:0051213],
Cellular Component:
nucleus [GO:0005634],
cytoplasm [GO:0005737],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
membrane [GO:0016020],