acireductone dioxygenase 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
29548335 Saos-2 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES
31983656 MSC Human YES

GO terms:

Biological Process:
methionine metabolic process [GO:0006555],
L-methionine biosynthetic process from methylthioadenosine [GO:0019509],
oxidation-reduction process [GO:0055114],
cellular amino acid biosynthetic process [GO:0008652],
methionine biosynthetic process [GO:0009086],

Molecular Function:
iron ion binding [GO:0005506],
protein binding [GO:0005515],
acireductone dioxygenase [iron(II)-requiring] activity [GO:0010309],
oxidoreductase activity [GO:0016491],
metal ion binding [GO:0046872],
dioxygenase activity [GO:0051213],

Cellular Component:
nucleus [GO:0005634],
cytoplasm [GO:0005737],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
membrane [GO:0016020],