alcohol dehydrogenase iron containing 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2 Human YES
30626320 HBEC Human NO

GO terms:

Biological Process:
glutamate catabolic process via 2-oxoglutarate [GO:0006539],
oxidation-reduction process [GO:0055114],
2-oxoglutarate metabolic process [GO:0006103],

Molecular Function:
alcohol dehydrogenase (NAD) activity [GO:0004022],
oxidoreductase activity [GO:0016491],
metal ion binding [GO:0046872],
hydroxyacid-oxoacid transhydrogenase activity [GO:0047988],

Cellular Component:
mitochondrion [GO:0005739],
mitochondrial matrix [GO:0005759],