ADH5
alcohol dehydrogenase 5 (class III), chi polypeptide
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 31945054 | IMR-90 | Human | YES | |
Status in senescence: Down-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 28844647 | BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 | Skin, Lung | Human | YES |
| 29581312 | HEK293, PCNs, MEF | Human, mouse | NO | |
| 31491600 | HAEC | Aorta | Human, mouse | NO |
GO terms:
Biological Process:
retinoid metabolic process [GO:0001523],
respiratory system process [GO:0003016],
ethanol oxidation [GO:0006069],
fatty acid omega-oxidation [GO:0010430],
peptidyl-cysteine S-nitrosylation [GO:0018119],
electron transport chain [GO:0022900],
response to lipopolysaccharide [GO:0032496],
positive regulation of blood pressure [GO:0045777],
formaldehyde catabolic process [GO:0046294],
response to nitrosative stress [GO:0051409],
response to redox state [GO:0051775],
ethanol catabolic process [GO:0006068],
Molecular Function:
alcohol dehydrogenase activity, zinc-dependent [GO:0004024],
fatty acid binding [GO:0005504],
zinc ion binding [GO:0008270],
electron carrier activity [GO:0009055],
formaldehyde dehydrogenase activity [GO:0018467],
identical protein binding [GO:0042802],
S-(hydroxymethyl)glutathione dehydrogenase activity [GO:0051903],
alcohol dehydrogenase (NAD) activity [GO:0004022],
oxidoreductase activity [GO:0016491],
metal ion binding [GO:0046872],
Cellular Component:
mitochondrion [GO:0005739],
cytosol [GO:0005829],
extracellular exosome [GO:0070062],
nucleus [GO:0005634],
cytoplasm [GO:0005737],