CIB2

calcium and integrin binding family member 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
27323328 Saos-2,H1299, HT18, MCF7, MDA-MB-231, Li-Fraumeni Human YES
29548335 Saos-2 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
positive regulation of cytosolic calcium ion concentration [GO:0007204],
photoreceptor cell maintenance [GO:0045494],
calcium ion homeostasis [GO:0055074],
cellular response to ATP [GO:0071318],

Molecular Function:
magnesium ion binding [GO:0000287],
integrin binding [GO:0005178],
calcium ion binding [GO:0005509],
protein binding [GO:0005515],
protein homodimerization activity [GO:0042803],
macromolecular complex binding [GO:0044877],
metal ion binding [GO:0046872],

Cellular Component:
photoreceptor outer segment [GO:0001750],
photoreceptor inner segment [GO:0001917],
cytoplasm [GO:0005737],
muscle tendon junction [GO:0005927],
neuromuscular junction [GO:0031594],
stereocilium [GO:0032420],
cuticular plate [GO:0032437],
sarcolemma [GO:0042383],
blood microparticle [GO:0072562],
plasma membrane [GO:0005886],
membrane [GO:0016020],
cell projection [GO:0042995],