ATP binding cassette subfamily A member 12

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
29548335 Saos-2 Human YES
30988157 IMR-90 Human YES

GO terms:

Biological Process:
lipid transport [GO:0006869],
positive regulation of cholesterol efflux [GO:0010875],
cellular homeostasis [GO:0019725],
keratinization [GO:0031424],
secretion by cell [GO:0032940],
phospholipid efflux [GO:0033700],
ceramide transport [GO:0035627],
surfactant homeostasis [GO:0043129],
regulated exocytosis [GO:0045055],
lung alveolus development [GO:0048286],
transmembrane transport [GO:0055085],
lipid homeostasis [GO:0055088],
establishment of skin barrier [GO:0061436],
protein localization to plasma membrane [GO:0072659],
positive regulation of protein localization to cell surface [GO:2000010],
keratinocyte differentiation [GO:0030216],

Molecular Function:
receptor binding [GO:0005102],
lipid transporter activity [GO:0005319],
protein binding [GO:0005515],
ATP binding [GO:0005524],
ATPase activity [GO:0016887],
lipid-transporting ATPase activity [GO:0034040],
apolipoprotein A-I receptor binding [GO:0034191],
ATPase activity, coupled to transmembrane movement of substances [GO:0042626],

Cellular Component:
cytoplasm [GO:0005737],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
integral component of membrane [GO:0016021],
intracellular membrane-bounded organelle [GO:0043231],
epidermal lamellar body [GO:0097209],
mitochondrial inner membrane [GO:0005743],