CHAF1B
chromatin assembly factor 1 subunit B
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 29548335 | Li Fraumeni | Human | YES | |
Status in senescence: Down-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 29321003 | Primary bronchial epithelial cells derived from lung | Human | YES | |
| 29449545 | HMEC, MRC5, IMR-90, GP293, WI-38, HUVEC | Human | NO | |
| 30987592 | MCF7 | Breast | Human | YES |
| 30988157 | IMR-90 | Human | YES | |
| 31945125 | Primary astrocytes derived from brain | Human | YES | |
GO terms:
Biological Process:
DNA replication [GO:0006260],
DNA repair [GO:0006281],
nucleosome assembly [GO:0006334],
DNA replication-dependent nucleosome assembly [GO:0006335],
cell cycle [GO:0007049],
chromatin assembly [GO:0031497],
cellular response to DNA damage stimulus [GO:0006974],
Molecular Function:
chromatin binding [GO:0003682],
protein binding [GO:0005515],
histone binding [GO:0042393],
unfolded protein binding [GO:0051082],
Cellular Component:
nuclear chromatin [GO:0000790],
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],
cytosol [GO:0005829],
macromolecular complex [GO:0032991],
CAF-1 complex [GO:0033186],