CEP57

centrosomal protein 57

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31983656 MSC Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 Skin, Lung Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
G2/M transition of mitotic cell cycle [GO:0000086],
spermatid development [GO:0007286],
fibroblast growth factor receptor signaling pathway [GO:0008543],
regulation of G2/M transition of mitotic cell cycle [GO:0010389],
microtubule anchoring [GO:0034453],
protein homooligomerization [GO:0051260],
ciliary basal body docking [GO:0097711],

Molecular Function:
protein binding [GO:0005515],
microtubule binding [GO:0008017],
fibroblast growth factor binding [GO:0017134],
protein homodimerization activity [GO:0042803],
gamma-tubulin binding [GO:0043015],
identical protein binding [GO:0042802],

Cellular Component:
nucleus [GO:0005634],
Golgi apparatus [GO:0005794],
centrosome [GO:0005813],
cytosol [GO:0005829],
microtubule [GO:0005874],
cytoplasm [GO:0005737],
cytoskeleton [GO:0005856],